Assessment of Airway Distensibility by the Forced Oscillation Technique: Reproducible and Potentially Simplifiable

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Assessment of Airway Distensibility by the Forced Oscillation Technique: Reproducible and Potentially Simplifiable

A non-invasive index of airway distensibility is required to track airway remodeling over time. The forced oscillation technique (FOT) provides such an index by measuring the change in respiratory system conductance at 5 Hz over the corresponding change in lung volume (ΔGrs5/ΔVL). To become useful clinically, this method has to be reproducible and easy to perform. The series of breathing maneuv...

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Effect of airway smooth muscle tone on airway distensibility measured by the forced oscillation technique in adults with asthma.

Airway distensibility appears to be unaffected by airway smooth muscle (ASM) tone, despite the influence of ASM tone on the airway diameter-pressure relationship. This discrepancy may be because the greatest effect of ASM tone on airway diameter-pressure behavior occurs at low transpulmonary pressures, i.e., low lung volumes, which has not been investigated. Our study aimed to determine the con...

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detection of airway partitioning following unilateral nasal stimulations by the forced oscillation technique in rats.

nasal mucosa has an extraordinary nerve supply with unique geometry that encompasses complex physiology. among these, side-specific predilections to the respiratory and autonomic centers are the interesting issues that have been raised about the consequences of the nasal irritations. the aim of the study was an evaluation of how intranasal stimulation influences lung mechanics and determines wh...

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Combined forced oscillation and forced expiration measurements in mice for the assessment of airway hyperresponsiveness

BACKGROUND Pulmonary function has been reported in mice using negative pressure-driven forced expiratory manoeuvres (NPFE) and the forced oscillation technique (FOT). However, both techniques have always been studied using separate cohorts of animals or systems. The objective of this study was to obtain NPFE and FOT measurements at baseline and following bronchoconstriction from a single cohort...

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Detection of airway partitioning following unilateral nasal stimulations by the forced oscillation technique in rats.

Nasal mucosa has an extraordinary nerve supply with unique geometry that encompasses complex physiology. Among these, side-specific predilections to the respiratory and autonomic centers are the interesting issues that have been raised about the consequences of the nasal irritations. The aim of the study was an evaluation of how intranasal stimulation influences lung mechanics and determines wh...

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ژورنال

عنوان ژورنال: Frontiers in Physiology

سال: 2017

ISSN: 1664-042X

DOI: 10.3389/fphys.2017.00223